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A Mechanism for the Synergistic Antimalarial Action of Atovaquone and Proguanil

A combination of atovaquone and proguanil has been found to be quite effective in treating malaria, with little evidence of the emergence of resistance when atovaquone was used as a single agent. We have examined possible mechanisms for the synergy between these two drugs. While proguanil by itself...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Srivastava, Indresh K., Vaidya, Akhil B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10348748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.6.1334
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