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Antimicrobial Activities and Postantibiotic Effects of Clarithromycin, 14-Hydroxy-Clarithromycin, and Azithromycin in Epithelial Cell Lining Fluid against Clinical Isolates of Haemophilus influenzae and Streptococcus pneumoniae

The antimicrobial activity of concentrations of selected macrolides found in epithelial cell lining fluid was investigated. Clarithromycin demonstrated greater potency and a significantly longer postantibiotic effect (PAE) than azithromycin against Streptococcus pneumoniae. Azithromycin displayed gr...

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Bibliographic Details
Main Authors: Bergman, Kimberly L., Olsen, Keith M., Peddicord, Tom E., Fey, Paul D., Rupp, Mark E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89263/
https://ncbi.nlm.nih.gov/pubmed/10223956
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