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Diversity of Substitutions within or Adjacent to Conserved Amino Acid Motifs of Penicillin-Binding Protein 2X in Cephalosporin-Resistant Streptococcus pneumoniae Isolates

The sequence of an approximately 1.1-kb DNA fragment of the pbp2x gene, which encodes the transpeptidase domain, was determined for 35 clinical isolates of Streptococcus pneumoniae for which the cefotaxime (CTX) MICs varied. Strains with substitutions within a conserved amino acid motif changing STM...

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Autors principals: Asahi, Yasuko, Takeuchi, Yasuo, Ubukata, Kimiko
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89251/
https://ncbi.nlm.nih.gov/pubmed/10223944
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