The Immune Response Modifier Imiquimod Requires STAT-1 for induction of Interferon, Interferon-Stimulated Genes, and Interleukin-6

Imiquimod is an oral inducer of interferon (IFN) and several other proinflammatory cytokines and has been successfully used topically as an antiviral agent for the treatment of genital warts. We have investigated the molecular mechanisms by which imiquimod induces the expression of IFNs, IFN-stimula...

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Bibliographic Details
Main Authors: Bottrel, Renata L. A., Yang, Yi-Li, Levy, David E., Tomai, Mark, Reis, Luiz F. L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89217/
https://ncbi.nlm.nih.gov/pubmed/10103191
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