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Efficacy of RD3-0028 Aerosol Treatment against Respiratory Syncytial Virus Infection in Immunosuppressed Mice

RD3-0028, a benzodithiin compound, has antiviral activity against respiratory syncytial virus (RSV) in cell culture. We used a mouse model of RSV infection to determine the in vivo effect of RD3-0028. Cyclophosphamide (CYP)-treated, immunosuppressed mice were inoculated intranasally. The lungs of th...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Sudo, Kenji, Watanabe, Wataru, Konno, Kenji, Sato, Ryu, Kajiyashiki, Tsuyoshi, Shigeta, Shiro, Yokota, Tomoyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.752
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