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Penetration of Meropenem in Lung, Bronchial Mucosa, and Pleural Tissues

Lung, bronchial mucosa, and pleural tissue samples were obtained from 14 patients undergoing lung surgery 1 to 5 h after administration of 1 g of meropenem. The mean (range) peak concentrations of meropenem were 3.9 (0.2 to 8.2), 6.6 (3.0 to 13.3), and 2.8 (0.6 to 7.8) mg/kg of tissue, respectively,...

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Detalhes bibliográficos
Main Authors: Byl, Baudouin, Jacobs, Frédérique, Roucloux, Ingrid, de Franquen, Philippe, Cappello, Matteo, Thys, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89181/
https://ncbi.nlm.nih.gov/pubmed/10049288
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