Efflux-Mediated Aminoglycoside and Macrolide Resistance in Burkholderia pseudomallei

Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a wide range of antimicrobial agents including β-lactams, aminoglycosides, macrolides, and polymyxins. We used Tn5-OT182 to mutagenize B. pseudomallei to identify the genes involved in aminoglycoside resista...

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Bibliographic Details
Main Authors: Moore, Richard A., DeShazer, David, Reckseidler, Shauna, Weissman, Ania, Woods, Donald E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89145/
https://ncbi.nlm.nih.gov/pubmed/10049252
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