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Selective Effect of 2′,6′-Dihydroxy-4′-Methoxychalcone Isolated from Piper aduncum on Leishmania amazonensis

2′,6′-Dihydroxy-4′-methoxychalcone (DMC) was purified from the dichloromethane extract of Piper aduncum inflorescences. DMC showed significant activity in vitro against promastigotes and intracellular amastigotes of Leishmania amazonensis, with 50% effective doses of 0.5 and 24 μg/ml, respectively....

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Bibliografische gegevens
Hoofdauteurs: Torres-Santos, Eduardo Caio, Moreira, Davyson Lima, Kaplan, Maria Auxiliadora C., Meirelles, Maria Nazareth, Rossi-Bergmann, Bartira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89139/
https://ncbi.nlm.nih.gov/pubmed/10223942
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