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Pharmacodynamics of Trovafloxacin, Ofloxacin, and Ciprofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model

An in vitro pharmacokinetic model was used to simulate the pharmacokinetics of trovafloxacin, ofloxacin, and ciprofloxacin in human serum and to compare their pharmacodynamics against eight Streptococcus pneumoniae strains. The MICs of ofloxacin and ciprofloxacin ranged from 1 to 2 μg/ml. Trovafloxa...

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Main Authors: Lister, Philip D., Sanders, Christine C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC89120/
https://ncbi.nlm.nih.gov/pubmed/10223923
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