Negative Regulation of the Pseudomonas aeruginosa Outer Membrane Porin OprD Selective for Imipenem and Basic Amino Acids

Pseudomonas aeruginosa OprD is a specific porin which facilitates the uptake of basic amino acids and imipenem, a carbapenem antibiotic. Resistance to imipenem due to the loss of OprD is an important mechanism for the loss of clinical effectiveness. To investigate the negative regulatory mechanisms...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ochs, Martina M., McCusker, Matthew P., Bains, Manjeet, Hancock, Robert E. W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1085
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