Mutations in 23S rRNA in Helicobacter pylori Conferring Resistance to Erythromycin Do Not Always Confer Resistance to Clarithromycin

Mutations conferring resistance to erythromycin or clarithromycin in Helicobacter pylori were studied. Mutation A2142G was consistently associated with clarithromycin MIC of >256 μg/ml, whereas mutants carrying A2143G had MICs ranging from ≤0.016 to >256 μg/ml, suggesting that additional facto...

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Main Authors: García-Arata, M. Isabel, Baquero, Fernando, de Rafael, Luis, de Argila, Carlos Martín, Gisbert, Javier P., Bermejo, Fernando, Boixeda, Daniel, Cantón, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89082/
https://ncbi.nlm.nih.gov/pubmed/9925537
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