Fungal Lethality, Binding, and Cytotoxicity of Syringomycin-E

Syringomycin-E (SE) was significantly lethal to Aspergillus and Fusarium species at between 1.9 and 7.8 μg/ml. SE complexed with the following fungal wall constituents (in order of binding): β-1,3-glucan > chitin > mannan > ergosterol = cholesterol. Cytotoxicity in HeLa cells was proportion...

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Main Authors: De Lucca, A. J., Jacks, T. J., Takemoto, J., Vinyard, B., Peter, J., Navarro, E., Walsh, T. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89081/
https://ncbi.nlm.nih.gov/pubmed/9925536
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