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Effects of NorA Inhibitors on In Vitro Antibacterial Activities and Postantibiotic Effects of Levofloxacin, Ciprofloxacin, and Norfloxacin in Genetically Related Strains of Staphylococcus aureus

NorA is a membrane-associated multidrug efflux protein that can decrease susceptibility to fluoroquinolones in Staphylococcus aureus. To determine the effect of NorA inhibition on the pharmacodynamics of fluoroquinolones, we evaluated the activities of levofloxacin, ciprofloxacin, and norfloxacin wi...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Aeschlimann, Jeffrey R., Dresser, Linda D., Kaatz, Glenn W., Rybak, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925528/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.335
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