Amphotericin B and Fluconazole Affect Cellular Charge, Macrophage Phagocytosis, and Cellular Morphology of Cryptococcus neoformans at Subinhibitory Concentrations

Amphotericin B (AmB) and fluconazole (FLU) are the major antifungal drugs used in the treatment of cryptococcosis. Both drugs are believed to exert their antifungal effects through actions on cell membrane sterols. In this study we investigated whether AmB and FLU had other, more subtle effects on C...

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Bibliographic Details
Main Authors: Nosanchuk, Joshua D., Cleare, Wendy, Franzot, Sarah P., Casadevall, Arturo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89056/
https://ncbi.nlm.nih.gov/pubmed/9925511
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