Altered Extracellular Signal-Regulated Kinase Signaling and Glycogen Metabolism in Skeletal Muscle from p90 Ribosomal S6 Kinase 2 Knockout Mice

The p90 ribosomal S6 kinase (RSK), a cytosolic substrate for the extracellular signal-regulated kinase (ERK), is involved in transcriptional regulation, and one isoform (RSK2) has been implicated in the activation of glycogen synthase by insulin. To determine RSK2 function in vivo, mice lacking a fu...

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Autors principals: Dufresne, Scott D., Bjørbæk, Christian, El-Haschimi, Karim, Zhao, Yi, Aschenbach, William G., Moller, David E., Goodyear, Laurie J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC88782/
https://ncbi.nlm.nih.gov/pubmed/11113183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.81-87.2001
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