Comparison of Sequence Analysis and the INNO-LiPA HBV DR Line Probe Assay for Detection of Lamivudine-Resistant Hepatitis B Virus Strains in Patients under Various Clinical Conditions

A line probe assay (INNO-LiPA HBV DR) detecting drug-resistant hepatitis B virus (HBV) strains was evaluated. Results concordant with sequence analysis were obtained with 48 of 56 serum samples from HBV-infected patients undergoing lamivudine therapy. In eight cases, additional minor subpopulations...

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Autors principals: Aberle, Stephan W., Kletzmayr, Josef, Watschinger, Bruno, Schmied, Brigitte, Vetter, Norbert, Puchhammer-Stöckl, Elisabeth
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Virology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC88061/
https://ncbi.nlm.nih.gov/pubmed/11326026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.5.1972-1974.2001
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