Monitoring the Emergence of Hepatitis B Virus Polymerase Gene Variants during Lamivudine Therapy Using the LightCycler

Treatment of chronic hepatitis B virus (HBV) infection with lamivudine is associated with the appearance in the circulation of HBV variants with mutations in the YMDD (tyrosine, methionine, aspartate, aspartate) motif of the polymerase gene. Fluorometric real-time PCR with the LightCycler assay was...

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Autors principals: Whalley, Simon A., Brown, Dave, Teo, Chong Gee, Dusheiko, Geoffrey M., Saunders, Nicholas A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Virology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87954/
https://ncbi.nlm.nih.gov/pubmed/11283071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.4.1456-1459.2001
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