Rapid Detection of Mutations in the 23S rRNA Gene of Helicobacter pylori That Confers Resistance to Clarithromycin Treatment to the Bacterium

We developed a new method capable of detecting point mutations in the 23S rRNA gene of Helicobacter pylori using a LightCycler. Our method can detect a mutation in this gene in less than 1 h and can process many samples at once, thereby contributing to the selection of patients suitable for clarithr...

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Autors principals: Matsumura, Masayuki, Hikiba, Yoko, Ogura, Keiji, Togo, Goichi, Tsukuda, Izumi, Ushikawa, Kenji, Shiratori, Yasushi, Omata, Masao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Bacteriology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87798/
https://ncbi.nlm.nih.gov/pubmed/11158129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.2.691-695.2001
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