A Point Mutation in the N-Terminal Coiled-Coil Domain Releases c-Fes Tyrosine Kinase Activity and Survival Signaling in Myeloid Leukemia Cells

The c-fes locus encodes a 93-kDa non-receptor protein tyrosine kinase (Fes) that regulates the growth and differentiation of hematopoietic and vascular endothelial cells. Unique to Fes is a long N-terminal sequence with two regions of strong homology to coiled-coil oligomerization domains. We introd...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Cheng, Haiyun Y., Schiavone, Anthony P., Smithgall, Thomas E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87334/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11509660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.18.6170-6180.2001
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