Transcriptional Hyperactivity of Human Progesterone Receptors Is Coupled to Their Ligand-Dependent Down-Regulation by Mitogen-Activated Protein Kinase-Dependent Phosphorylation of Serine 294

Breast cancers often exhibit elevated expression of tyrosine kinase growth factor receptors; these pathways influence breast cancer cell growth in part by targeting steroid hormone receptors, including progesterone receptors (PR). To mimic activation of molecules downstream of growth factor-initiate...

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Detalhes bibliográficos
Main Authors: Shen, Tianjie, Horwitz, Kathryn B., Lange, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87329/
https://ncbi.nlm.nih.gov/pubmed/11509655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6122-6131.2001
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