Oncogenic Mutants of RON and MET Receptor Tyrosine Kinases Cause Activation of the β-Catenin Pathway

β-Catenin is an oncogenic protein involved in regulation of cell-cell adhesion and gene expression. Accumulation of cellular β-catenin occurs in many types of human cancers. Four mechanisms are known to cause increases in β-catenin: mutations of β-catenin, adenomatous polyposis coli, or axin genes a...

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Bibliographische Detailangaben
Hauptverfasser: Danilkovitch-Miagkova, Alla, Miagkov, Alexei, Skeel, Alison, Nakaigawa, Noboru, Zbar, Berton, Leonard, Edward J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87305/
https://ncbi.nlm.nih.gov/pubmed/11486025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5857-5868.2001
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