Role of Phosphoinositide 3-Kinase in the Aggressive Tumor Growth of HT1080 Human Fibrosarcoma Cells

We have developed a model system of human fibrosarcoma cell lines that do or do not possess and express an oncogenic mutant allele of N-ras. HT1080 cells contain an endogenous mutant allele of N-ras, whereas the derivative MCH603 cell line contains only wild-type N-ras. In an earlier study (S. Gupta...

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Hlavní autoři: Gupta, Swati, Stuffrein, Selma, Plattner, Rina, Tencati, Michael, Gray, Christa, Whang, Young E., Stanbridge, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87304/
https://ncbi.nlm.nih.gov/pubmed/11486024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5846-5856.2001
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