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Promoter Clearance by RNA Polymerase II Is an Extended, Multistep Process Strongly Affected by Sequence

We have characterized RNA polymerase II complexes halted from +16 to +49 on two templates which differ in the initial 20 nucleotides (nt) of the transcribed region. On a template with a purine-rich initial transcript, most complexes halted between +20 and +32 become arrested and cannot resume RNA sy...

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Autors principals: Pal, Mahadeb, McKean, David, Luse, Donal S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87301/
https://ncbi.nlm.nih.gov/pubmed/11486021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5815-5825.2001
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