Loss of Cell Cycle Checkpoint Control in Drosophila Rfc4 Mutants

Two alleles of the Drosophila melanogaster Rfc4 (DmRfc4) gene, which encodes subunit 4 of the replication factor C (RFC) complex, cause striking defects in mitotic chromosome cohesion and condensation. These mutations produce larval phenotypes consistent with a role in DNA replication but also resul...

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Bibliographic Details
Main Authors: Krause, Sue A., Loupart, Marie-Louise, Vass, Sharron, Schoenfelder, Stefan, Harrison, Steve, Heck, Margarete M. S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC87240/
https://ncbi.nlm.nih.gov/pubmed/11438670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5156-5168.2001
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