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Loss of Cell Cycle Checkpoint Control in Drosophila Rfc4 Mutants

Two alleles of the Drosophila melanogaster Rfc4 (DmRfc4) gene, which encodes subunit 4 of the replication factor C (RFC) complex, cause striking defects in mitotic chromosome cohesion and condensation. These mutations produce larval phenotypes consistent with a role in DNA replication but also resul...

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Udgivet i:Mol Cell Biol
Principais autores: Krause, Sue A., Loupart, Marie-Louise, Vass, Sharron, Schoenfelder, Stefan, Harrison, Steve, Heck, Margarete M. S.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87240/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438670/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.15.5156-5168.2001
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