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Ligand-Dependent Degradation of Retinoid X Receptors Does Not Require Transcriptional Activity or Coactivator Interactions

Cells utilize ubiquitin-mediated proteolysis to regulate the activity of numerous proteins involved in signal transduction, cell cycle control, and transcriptional regulation. For a number of transcription factors, there appears to be a direct correlation between transcriptional activity and protein...

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Udgivet i:Mol Cell Biol
Principais autores: Osburn, Deborah L., Shao, Gang, Seidel, H. Martin, Schulman, Ira G.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87210/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.15.4909-4918.2001
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