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The MLK Family Mediates c-Jun N-Terminal Kinase Activation in Neuronal Apoptosis

Neuronal apoptotic death induced by nerve growth factor (NGF) deprivation is reported to be in part mediated through a pathway that includes Rac1 and Cdc42, mitogen-activated protein kinase kinases 4 and 7 (MKK4 and -7), c-Jun N-terminal kinases (JNKs), and c-Jun. However, additional components of t...

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Bibliografiske detaljer
Main Authors: Xu, Zhiheng, Maroney, Anna C., Dobrzanski, Pawel, Kukekov, Nickolay V., Greene, Lloyd A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87148/
https://ncbi.nlm.nih.gov/pubmed/11416147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4713-4724.2001
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