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Bmx Tyrosine Kinase Has a Redundant Function Downstream of Angiopoietin and Vascular Endothelial Growth Factor Receptors in Arterial Endothelium

The Bmx gene, a member of the Tec tyrosine kinase gene family, is known to be expressed in subsets of hematopoietic and endothelial cells. In this study, mice were generated in which the first coding exon of the Bmx gene was replaced with the lacZ reporter gene by a knock-in strategy. The homozygous...

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Published in:Mol Cell Biol
Main Authors: Rajantie, Iiro, Ekman, Niklas, Iljin, Kristiina, Arighi, Elena, Gunji, Yuji, Kaukonen, Jaakko, Palotie, Aarno, Dewerchin, Mieke, Carmeliet, Peter, Alitalo, Kari
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.14.4647-4655.2001
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