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The EphA8 Receptor Regulates Integrin Activity through p110γ Phosphatidylinositol-3 Kinase in a Tyrosine Kinase Activity-Independent Manner
Recent genetic studies suggest that ephrins may function in a kinase-independent Eph receptor pathway. Here we report that expression of EphA8 in either NIH 3T3 or HEK293 cells enhanced cell adhesion to fibronectin via α(5)β(1)- or β(3) integrins. Interestingly, a kinase-inactive EphA8 mutant also m...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87117/ https://ncbi.nlm.nih.gov/pubmed/11416136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4579-4597.2001 |
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