Deubiquitination Step in the Endocytic Pathway of Yeast Plasma Membrane Proteins: Crucial Role of Doa4p Ubiquitin Isopeptidase

The Fur4p uracil permease, like most yeast plasma membrane proteins, undergoes ubiquitin-dependent endocytosis and is then targeted to the vacuole (equivalent to the mammalian lysosome) for degradation. The cell surface ubiquitination of Fur4p is mediated by the essential Rsp5p ubiquitin ligase. Ubi...

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Bibliographic Details
Main Authors: Dupré, S., Haguenauer-Tsapis, R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Cell and Organelle Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC87108/
https://ncbi.nlm.nih.gov/pubmed/11416128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4482-4494.2001
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