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Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells

Studies with live cells demonstrate that agonist and antagonist rapidly (within minutes) modulate the subnuclear dynamics of estrogen receptor α (ER) and steroid receptor coactivator 1 (SRC-1). A functional cyan fluorescent protein (CFP)-tagged lac repressor-ER chimera (CFP-LacER) was used in live c...

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Published in:Mol Cell Biol
Main Authors: Stenoien, David L., Nye, Anne C., Mancini, Maureen G., Patel, Kavita, Dutertre, Martin, O'Malley, Bert W., Smith, Carolyn L., Belmont, Andrew S., Mancini, Michael A.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4404-4412.2001
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