Early Virological Failure in Naive Human Immunodeficiency Virus Patients Receiving Saquinavir (Soft Gel Capsule)-Stavudine-Zalcitabine (MIKADO Trial) Is Not Associated with Mutations Conferring Viral Resistance

The MIKADO trial was designed to evaluate the efficacy of stavudine-zalcitabine-saquinavir (soft gel capsule) [d4T-ddC-SQV(SGC)] in 36 naive patients (−3.3 log(10) units at week 24 [W24]). Among the 29 patients remaining on d4T-ddC-SQV(SGC) until W24, 10 harbored a virological failure (viral load of...

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Pubblicato in:	J Clin Microbiol
Autori principali:	Mouroux, M., Yvon-Groussin, A., Peytavin, G., Delaugerre, C., Legrand, M., Bossi, P., Do, B., Trylesinski, A., Diquet, B., Dohin, E., Delfraissy, J. F., Katlama, C., Calvez, V.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Virology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10878071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.38.7.2726-2730.2000
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