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Interaction of Eukaryotic Translation Initiation Factor 4G with the Nuclear Cap-Binding Complex Provides a Link between Nuclear and Cytoplasmic Functions of the m(7) Guanosine Cap

In eukaryotes the majority of mRNAs have an m(7)G cap that is added cotranscriptionally and that plays an important role in many aspects of mRNA metabolism. The nuclear cap-binding complex (CBC; consisting of CBP20 and CBP80) mediates the stimulatory functions of the cap in pre-mRNA splicing, 3′ end...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: McKendrick, Linda, Thompson, Elizabeth, Ferreira, Joao, Morley, Simon J., Lewis, Joe D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2001
Schlagworte:
Nucleocytoplasmic Communication
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11340157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.11.3632-3641.2001
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