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Requirement for p27(KIP1) in Retinoblastoma Protein-Mediated Senescence

In vivo and in vitro evidence indicate that cells do not divide indefinitely but instead stop growing and undergo a process termed cellular proliferative senescence. Very little is known about how senescence occurs, but there are several indications that the retinoblastoma protein (pRb) is involved,...

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Detalhes bibliográficos
Main Authors: Alexander, Kamilah, Hinds, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86983/
https://ncbi.nlm.nih.gov/pubmed/11340156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.11.3616-3631.2001
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