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Role of NF-Y in In Vivo Regulation of the γ-Globin Gene
The duplicated CCAAT box is required for γ gene expression. We report here that the transcriptional factor NF-Y is recruited to the duplicated CCAAT box in vivo. A mutation of the duplicated CCAAT box that severely disrupts the NF-Y binding also reduces the accessibility level of the γ gene promoter...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86936/ https://ncbi.nlm.nih.gov/pubmed/11287613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3083-3095.2001 |
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