Role of NF-Y in In Vivo Regulation of the γ-Globin Gene

The duplicated CCAAT box is required for γ gene expression. We report here that the transcriptional factor NF-Y is recruited to the duplicated CCAAT box in vivo. A mutation of the duplicated CCAAT box that severely disrupts the NF-Y binding also reduces the accessibility level of the γ gene promoter...

Full description

Saved in:
Bibliographic Details
Main Authors: Duan, Zhijun, Stamatoyannopoulos, George, Li, Qiliang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86936/
https://ncbi.nlm.nih.gov/pubmed/11287613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3083-3095.2001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items