Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains

CIITA is the master regulator of class II major histocompatibility complex gene expression. We present evidence that CIITA can self-associate via two domains: the C terminus (amino acids 700 to 1130) and the GTP-binding domain (amino acids 336 to 702). Heterotypic and homotypic interactions are obse...

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Autores principales: Linhoff, Michael W., Harton, Jonathan A., Cressman, Drew E., Martin, Brian K., Ting, Jenny Pan-Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC86929/
https://ncbi.nlm.nih.gov/pubmed/11287606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3001-3011.2001
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