Two Distinct Domains within CIITA Mediate Self-Association: Involvement of the GTP-Binding and Leucine-Rich Repeat Domains

CIITA is the master regulator of class II major histocompatibility complex gene expression. We present evidence that CIITA can self-associate via two domains: the C terminus (amino acids 700 to 1130) and the GTP-binding domain (amino acids 336 to 702). Heterotypic and homotypic interactions are obse...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Linhoff, Michael W., Harton, Jonathan A., Cressman, Drew E., Martin, Brian K., Ting, Jenny Pan-Yun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86929/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.3001-3011.2001
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