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runt Homology Domain Transcription Factors (Runx, Cbfa, and AML) Mediate Repression of the Bone Sialoprotein Promoter: Evidence for Promoter Context-Dependent Activity of Cbfa Proteins

Expression of the bone sialoprotein (BSP) gene, a marker of bone formation, is largely restricted to cells in mineralized tissues. Recent studies have shown that the Cbfa1 (also known as Runx2, AML-3, and PEBP2αA) transcription factor supports commitment and differentiation of progenitor cells to hy...

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Udgivet i:Mol Cell Biol
Principais autores: Javed, Amjad, Barnes, George L., Jasanya, B. O., Stein, Janet L., Gerstenfeld, Louis, Lian, Jane B., Stein, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.8.2891-2905.2001
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