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The Insert Region of Rac1 Is Essential for Membrane Ruffling but Not Cellular Transformation

The Rho family of Ras-related proteins, which includes Rac1, RhoA, and Cdc42, is distinguished from other members of the Ras superfamily of small GTPases in that its members possess additional sequences positioned between β-strand 5 and α-helix 4, designated the insert region. Previous studies have...

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Autors principals: Karnoub, Antoine E., Der, Channing J., Campbell, Sharon L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86914/
https://ncbi.nlm.nih.gov/pubmed/11283263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2847-2857.2001
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