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Reduction of Target Gene Expression by a Modified U1 snRNA

Although the primary function of U1 snRNA is to define the 5′ donor site of an intron, it can also block the accumulation of a specific RNA transcript when it binds to a donor sequence within its terminal exon. This work was initiated to investigate if this property of U1 snRNA could be exploited as...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Beckley, S. A., Liu, P., Stover, M. L., Gunderson, S. I., Lichtler, A. C., Rowe, D. W.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.8.2815-2825.2001
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