Interleukin-1 (IL-1) Receptor-Associated Kinase Leads to Activation of TAK1 by Inducing TAB2 Translocation in the IL-1 Signaling Pathway

Interleukin-1 (IL-1) is a proinflammatory cytokine that recognizes a surface receptor complex and generates multiple cellular responses. IL-1 stimulation activates the mitogen-activated protein kinase kinase kinase TAK1, which in turn mediates activation of c-Jun N-terminal kinase and NF-κB. TAB2 ha...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Takaesu, Giichi, Ninomiya-Tsuji, Jun, Kishida, Satoshi, Li, Xiaoxia, Stark, George R., Matsumoto, Kunihiro
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.7.2475-2484.2001
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