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Identification of the Sin3-Binding Site in Ume6 Defines a Two-Step Process for Conversion of Ume6 from a Transcriptional Repressor to an Activator in Yeast

The DNA-binding protein Ume6 is required for both repression and activation of meiosis-specific genes, through interaction with the Sin3 corepressor and Rpd3 histone deacetylase and the meiotic activator Ime1. Here we show that fusion of a heterologous activation domain to Ume6 is unable to convert...

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Bibliografski detalji
Glavni autori: Washburn, Brian K., Esposito, Rochelle Easton
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86811/
https://ncbi.nlm.nih.gov/pubmed/11238941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2057-2069.2001
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