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Viral Cyclin–Cyclin-Dependent Kinase 6 Complexes Initiate Nuclear DNA Replication

The cyclins encoded by Kaposi sarcoma-associated herpesvirus and herpesvirus saimiri are homologs of human D-type cyclins. However, when complexed to cdk6, they have several activities that distinguish them from D-type cyclin-cdk6 complexes, including resistance to cyclin-dependent kinase inhibitors...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Laman, Heike, Coverley, Dawn, Krude, Torsten, Laskey, Ronald, Jones, Nic
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.624-635.2001
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