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Mice Devoid of Fer Protein-Tyrosine Kinase Activity Are Viable and Fertile but Display Reduced Cortactin Phosphorylation

The ubiquitous Fer protein-tyrosine kinase has been proposed to regulate diverse processes such as cell growth, cell adhesion, and neurite outgrowth. To gain insight into the biological function of Fer, we have targeted the fer locus with a kinase-inactivating missense mutation (fer(D743R)). Mice ho...

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Autori principali: Craig, Andrew W. B., Zirngibl, Ralph, Williams, Karen, Cole, Lesley-Ann, Greer, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86629/
https://ncbi.nlm.nih.gov/pubmed/11134346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.603-613.2001
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