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Id Helix-Loop-Helix Proteins Antagonize Pax Transcription Factor Activity by Inhibiting DNA Binding

The Id subfamily of helix-loop-helix (HLH) proteins plays a fundamental role in the regulation of cellular proliferation and differentiation. The major mechanism by which Id proteins are thought to inhibit differentiation is through interaction with other HLH proteins and inhibition of their DNA-bin...

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Autors principals: Roberts, E. Claire, Deed, Richard W., Inoue, Toshiaki, Norton, John D., Sharrocks, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86614/
https://ncbi.nlm.nih.gov/pubmed/11134340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.524-533.2001
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