Transforming Growth Factor β-Independent Shuttling of Smad4 between the Cytoplasm and Nucleus

Smad4 plays a pivotal role in all transforming growth factor β (TGF-β) signaling pathways. Here we describe six widely expressed alternatively spliced variants of human Smad4 with deletions of different exons in the linker, the region of Smad4 that separates the two well-conserved MH1 and MH2 domain...

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Bibliographic Details
Main Authors: Pierreux, Christophe E., Nicolás, Francisco J., Hill, Caroline S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Nucleocytoplasmic Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86557/
https://ncbi.nlm.nih.gov/pubmed/11074002
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