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8-Bromo-Cyclic AMP Induces Phosphorylation of Two Sites in SRC-1 That Facilitate Ligand-Independent Activation of the Chicken Progesterone Receptor and Are Critical for Functional Cooperation between SRC-1 and CREB Binding Protein

Elevation of intracellular 8-bromo-cyclic AMP (cAMP) can activate certain steroid receptors and enhance the ligand-dependent activation of most receptors. During ligand-independent activation of the chicken progesterone receptor (cPR(A)) with the protein kinase A (PKA) activator, 8-bromo-cAMP, we fo...

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Published in:Mol Cell Biol
Main Authors: Rowan, Brian G., Garrison, Nefretiti, Weigel, Nancy L., O'Malley, Bert W.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8720-8730.2000
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