Elevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis

The winged helix transcription factor, hepatocyte nuclear factor-3β (HNF-3β), mediates the hepatocyte-specific transcription of numerous genes important for liver function. However, the in vivo role of HNF-3β in regulating these genes remains unknown because homozygous null HNF3β mouse embryos die i...

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Hauptverfasser: Rausa, Francisco M., Tan, Yongjun, Zhou, Heping, Yoo, Kyung W., Stolz, Donna Beer, Watkins, Simon C., Franks, Roberta R., Unterman, Terry G., Costa, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86435/
https://ncbi.nlm.nih.gov/pubmed/11027295
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