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Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties

We deduced the structure of the mouse profilin II gene. It contains five exons that can generate four different transcripts by alternative splicing. Two transcripts encode different profilin II isoforms (designated IIa and IIb) that have similar affinities for actin but different affinities for poly...

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Main Authors: Lambrechts, Anja, Braun, Attila, Jonckheere, Veronique, Aszodi, Attila, Lanier, Lorene M., Robbens, Johan, Van Colen, Inge, Vandekerckhove, Joël, Fässler, Reinhard, Ampe, Christophe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC86430/
https://ncbi.nlm.nih.gov/pubmed/11027290
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