Multiple Mechanisms of Suppression Circumvent Transcription Defects in an RNA Polymerase Mutant

Using a high-copy-number suppressor screen to obtain clues about the role of the yeast RNA polymerase II subunit RPB4 in transcription, we identified three suppressors of the temperature sensitivity resulting from deletion of the RPB4 gene (ΔRPB4). One suppressor is Sro9p, a protein related to La pr...

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Main Authors: Tan, Qian, Li, Xin, Sadhale, Parag P., Miyao, Takenori, Woychik, Nancy A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
主題:
Transcriptional Regulation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC86422/
https://ncbi.nlm.nih.gov/pubmed/11027282
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