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Target Selectivity of Bicoid Is Dependent on Nonconsensus Site Recognition and Protein-Protein Interaction

We describe experiments to compare the activities of two Drosophila homeodomain proteins, Bicoid (Bcd) and an altered-specificity mutant of Fushi tarazu, Ftz(Q50K). Although the homeodomains of these proteins share a virtually indistinguishable ability to recognize a consensus Bcd site, only Bcd can...

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Udgivet i:Mol Cell Biol
Principais autores: Zhao, Chen, Dave, Vrushank, Yang, Fan, Scarborough, Tom, Ma, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.21.8112-8123.2000
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